Method of rare ginsenosides production using thermostable beta-glycosidase

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PURPOSE : A composition for preparing rear ginsenoside using beta-glycosidase and a method for preparing the ginsenoside are provided to quickly and selectively convert ginsenoside to other material.CONSTITUTION : A composition for preparing rare ginsenoside contains beta-glycosidase of high temperature. The rare ginsenosdie contains compound K, Y or Mc. The optically active temperature of the beta-glycosidase is 70-100°C. The beta-glycosidase is derived from Sulfolobus acidocaldarius. The beta-glycosidase has an amino acid of sequence number 4. The rear ginsenoside is obtained by reacting the beta-glycosidase with ginsenoside Rb1, Rb2, Rc or Rd and mixture in a reaction solvent at pH 4.5-7.0 and 70-100°C.COPYRIGHT KIPO 2011