GENOME-WIDE ASSOCIATION STUDY OF AUTISM REVEALS A COMNON NOVEL RISK LOCUS AT 5P14.1

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A genome wide association analysis demonstrates that in addition to multiple rare variations, part of the complex genetic architecture of autism involves common variation. Biomarkers identified as being associated with autisms or autism spectrum of disorders include single nucleotide polymorphisms (SNPs) which demonstrated strong association with autism risk. A novel region on chromosome 5pl4.1 was also identified which showed significance in both the discovery and validation datasets.