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NANOPARTICLE FOR DUAL MODAL IMAGING BY FLUORESCENCE AND MAGNETIC RESONANCE AND METHOD FOR PRODUCING

2025-06-20 05:182150下载
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PROBLEM TO BE SOLVED : To provide new nanoparticles having a positive contrast function for MRI and a method for producing the same, and to further provide new nanoparticles having two functions of near-infrared fluorescence and magnetic resonance imaging ability. SOLUTION : The nanoparticles having a positive contrast agent function for MRI are obtained by using YAG nanoparticles having a garnet structure as a matrix and allowing gadolinium (Gd) to exist locally on surfaces thereof. A probe having two functions of near-infrared fluorescence and magnetic resonance imaging ability can be obtained by converting the YAG nanoparticles as a matrix to a solid solution doped with a rare earth metal such as Yb3+. COPYRIGHT : (C)2010, JPO&INPIT


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