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PHARMACEUTICAL COMPOUNDS

2025-06-18 19:364680下载
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Nonane and decane diazabicyclic derivatives having homopiperazine as main ring, having affinity for the opioidergic µ and/or .delta. and/or k receptors and/or for all their receptorial subclasses, with central and/or peripheral activity, having formula (I), the isomeric forms and their mixtures included, wherein one or more atoms are in the corresponding isotopic forms : (see formula I) wherein : - n is an integer equal to 1 or 2; - one of the substituents R and R1 of the nitrogen atoms of the di-- azabicyclic ring is a -C(O)-R B group, wherein R B is a C1-C10 alkyl group, linear or branched when possible, - the other remained substituent of R and R1 has the meanings re--ported in the description.


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