RNAI AGENTS FOR ANTI-SARS CORONAVIRUS THERAPY

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The present invention provides compositions and methods that are useful for the treatment of severe acute respiratory syndrome (SARS). More specifically , nucleic acid agents such as siRNA molecules and their analogues that target respiratory infections including SARS coronavirus and their methods of use a re described, for clinical treatments of SARS, respiratory viral infections, fo r prevention and treatment of respiratory infections as needed for bio-defense , for treatment of respiratory diseases, and for discovery of therapeutic targets for respiratory diseases and infections.