COMPOUNDS WITH MDR1-INVERSE ACTIVITY

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Disclosed herein are drug compounds that have MDR-inverse activity and thus are effective against multidrug-re-sistant cells. Exemplary compounds disclosed herein have the following structure : (I). Examples of the disclosed compounds have been found to have, inter alia, efficacy in directly treating multidrug resistant cells, rendering multidrug resistant cells susceptible to other chemotherapeutics and in some instances reversing multidrug resistance.